产品名称
NMB Rabbit Polyclonal Antibody
蛋白名称
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P08949
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P08949/entry
Mouse Swissprot No.
Q9CR53
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CR53
免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
NMB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],
组织表达
Brain,Hypothalamus,Ovary,
细胞定位
Secreted . Cell projection, neuron projection . In neurons of the retrotrapezoid nucleus//parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex. .
功能
function:Stimulates smooth muscle contraction in a manner similar to that of bombesin.,similarity:Belongs to the bombesin/neuromedin-B/ranatensin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
