产品名称
ATAD2 (6E6) Rabbit Monoclonal Antibody
别名
ANCCA; Atad2; CT137; L16; PRO2000;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q6PL18
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50
注意事项
ATAD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
功能
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
