产品名称
KHSRP (4N5) Rabbit Monoclonal Antibody
别名
FBP2; FUBP2; KHSRP; KSRP; p75;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q92945
免疫原
A synthetic peptide of human KHSRP
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:1000
注意事项
KHSRP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in neural and non-neural cell lines.
细胞定位
Nucleus. Cytoplasm. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites.
功能
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue- specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
