产品名称
Fbx32 (2X3) Rabbit Monoclonal Antibody
别名
Atrogin 1; ATROGIN1; fbxo25; FBXO32; MAFbx;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q969P5
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200
注意事项
Fbx32 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Specifically expressed in cardiac and skeletal muscle
细胞定位
Cytoplasm. Nucleus Note=Shuttles between cytoplasm and the nucleus
功能
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
