RM5986

CBS (11I11) Rabbit Monoclonal Antibody

HIP4; CBS;

Affinity-chromatography

常规抗体

CBS

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

102724560;875

P35520

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

61kDa

Rabbit IgG

CBS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney

Cytoplasm. Nucleus

Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).

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