产品名称
TTC11 (18H3) Rabbit Monoclonal Antibody
别名
CGI135; FIS1; hFis1; TTC 11;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9Y3D6
免疫原
A synthetic peptide of human TTC11
稀释度
WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20
注意事项
TTC11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein
功能
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
