RM5973

E2F4 (15B9) Rabbit Monoclonal Antibody

E2F 4; E2F transcription factor 4; E2F transcription factor 4 p107/p130 binding; E2F4;

Affinity-chromatography

常规抗体

E2F4

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

1874

Q16254

A synthetic peptide of human E2F4

WB: 1:1000-1:5000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200 FC: 1:20

65kDa

44kDa

Rabbit IgG

E2F4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas

Nucleus.

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

现货