产品名称
PERP (11A7) Rabbit Monoclonal Antibody
别名
KCP1; KRTCAP1; Perp; PIGPC1; THW;
纯度
Affinity-chromatography
蛋白名称
KCP1, KRTCAP1, PIGPC1, THW
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q96FX8
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200
注意事项
PERP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts
细胞定位
Cell junction, desmosome {ECO:0000250|UniProtKB:Q9JK95}. Cell membrane {ECO:0000250|UniProtKB:Q9JK95}; Multi-pass membrane protein. Note=Associated with desmosomes {ECO:0000250|UniProtKB:Q9JK95}
功能
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).
