产品名称
MGEA5 (10M9) Rabbit Monoclonal Antibody
别名
HEXC; MEA5; Mgea5; NCOAT; OGA;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O60502
稀释度
WB 1:1000~1:5000 IHC 1:50~1:200 IP 1:80
注意事项
MGEA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitous. Shows highest expression in the brain, placenta and pancreas.
细胞定位
[Isoform 3]: Nucleus
功能
[Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:
11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:
24088714).