RM5897

PMP70 (6N3) Rabbit Monoclonal Antibody

ABCD3; ABC43; PMP70; PXMP1; ZWS2;

Affinity-chromatography

常规抗体

ABCD3

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

5825

P28288

A synthetic peptide of human PMP70

WB: 1:1000-1:5000 ICC/IF: 1:200 FC: 1:100-1:200

70kDa

76kDa

Rabbit IgG

PMP70 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Peroxisome membrane; Multi-pass membrane protein

Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long- chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched- chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed:11248239, PubMed:25168382, PubMed:24333844, PubMed:29397936). Has fatty acyl-CoA thioesterase and ATPase activities (PubMed:29397936). Probably hydrolyzes fatty acyl- CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity). Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:25944712, PubMed:24333844).

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