产品名称
p150 CAF1 (19O17) Rabbit Monoclonal Antibody
别名
CAF; CAF1; CAF1P150; CHAF1A; DCAF1; hp15; P150;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q13111
免疫原
A synthetic peptide of human p150 CAF1
稀释度
WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 FC: 1:200-1:1000 IP: 1:20
注意事项
p150 CAF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Note=DNA replication foci
功能
Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
