产品名称
LY75 (12P8) Rabbit Monoclonal Antibody
别名
CD205; CLEC13B; DEC-205; gp200-MR6; Ly-75; LY75;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
100526664;4065
Human Swissprot No.
O60449
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
注意事项
LY75 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells
细胞定位
Membrane; Single-pass type I membrane protein
功能
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B- lymphocytes.
