产品名称
CD89 (10E10) Rabbit Monoclonal Antibody
别名
CD89; Fc alpha receptor; FCAR; IgA Fc receptor;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P24071
稀释度
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:100~1:500 IP 1:50 FC 1:50
注意事项
CD89 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces
细胞定位
[Isoform A.1]: Cell membrane; Single-pass type I membrane protein [Isoform A.3]: Cell membrane; Single-pass type I membrane protein [Isoform B-delta-S2]: Secreted.
功能
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.