RM5843

BAP31 (1P10) Rabbit Monoclonal Antibody

BCR-associated protein Bap31; p28 Bap31; Protein CDM;

Affinity-chromatography

常规抗体

BCAP31

BAP31 {ECO:0000303|PubMed:25854864}, DXS

WB

Human,Mouse

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

10134

P51572

A synthetic peptide of human BAP31

WB: 1:1000-1:5000 IHC: 1:50-1:200 ICC/IF: 1:20-1:50 FC: 1:20-1:100

28kDa

28kDa

Rabbit IgG

BAP31 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Ubiquitous. Highly expressed in neurons and discrete endocrine cells.

Endoplasmic reticulum membrane; Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex (PubMed:9396746). Associates with the mitochondria-associated endoplasmic reticulum membrane via interaction with TOMM40 (PubMed:31206022)

Functions as a chaperone protein (PubMed:9396746, PubMed:18287538). Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, PubMed:18287538). Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, PubMed:18287538). Also serves as a cargo receptor for the export of transmembrane proteins (By similarity). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022). In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022). May be involved in CASP8-mediated apoptosis (PubMed:10958671).

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