RM5838

Lipin 1 (18K13) Rabbit Monoclonal Antibody

Lipin-1; Lpin1; PAP1;

Affinity-chromatography

常规抗体

LPIN1

KIAA0188

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

23175

Q14693

A synthetic peptide of human Lipin 1

WB: 1:1000-1:5000 IHC: 1:20-1:50 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20

130kDa

99kDa

Rabbit IgG

Lipin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Specifically expressed in skeletal muscle. Also abundant in adipose tissue. Lower levels in some portions of the digestive tract.

Nucleus membrane. Cytoplasm, cytosol. Endoplasmic reticulum membrane

Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels (PubMed:20231281). Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).

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