产品名称
Plexin A1 (3J3) Rabbit Monoclonal Antibody
别名
NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9UIW2
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50
注意事项
Plexin A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in fetal brain, lung, liver and kidney.
细胞定位
Cell membrane; Single-pass type I membrane protein
功能
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
