RM5832

Plexin A1 (3J3) Rabbit Monoclonal Antibody

NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1;

Affinity-chromatography

常规抗体

PLXNA1

NOV, PLXN1

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

5361

Q9UIW2

WB 1:500-2000

211kDa

Rabbit IgG

Plexin A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Detected in fetal brain, lung, liver and kidney.

Cell membrane; Single-pass type I membrane protein

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

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