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RHEB (18Y18) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5815
产品名称
RHEB (18Y18) Rabbit Monoclonal Antibody
别名
RHEB 2; Rheb; RHEB2;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
RHEB
蛋白名称
RHEB2
推荐应用
WB
反应种属
Human
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
6009
Human Swissprot No.
Q15382
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:100
预测分子量
20kDa
同种型
Rabbit IgG
注意事项
RHEB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
细胞定位
Endomembrane system {ECO:0000269|PubMed:22002721, ECO:0000305}; Lipid-anchor {ECO:0000269|PubMed:22002721, ECO:0000305}; Cytoplasmic side {ECO:0000269|PubMed:15489334, ECO:0000305}. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side
功能
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
期货
现货

Western blot analysis of RHEB expression in Raji cell lysate.

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