RM5803

Retinoic Acid Receptor beta (13V4) Rabbit Monoclonal Antibody

HAP; NR1B2; RAR B; RAR beta; RAR epsilon; RARB; RRB2;

Affinity-chromatography

常规抗体

RARB

HAP, NR1B2

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

5915

P10826

A synthetic peptide of human Retinoic Acid Receptor beta

WB: 1:1000-1:5000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50

55kDa

51kDa

Rabbit IgG

Retinoic Acid Receptor beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in aortic endothelial cells (at protein level).

Nucleus. Cytoplasm [Isoform Beta-2]: Nucleus.

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed:12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed:29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

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