产品名称
Gelsolin (5B3) Rabbit Monoclonal Antibody
别名
ADF; AGEL; Brevin; Gelsolin; Gsn;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P06396
免疫原
A synthetic peptide of human Gelsolin
稀释度
WB: 1:2000-1:10000 IHC: 1:200-1:500
注意事项
Gelsolin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells
细胞定位
[Isoform 2]: Cytoplasm, cytoskeleton.
功能
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
