RM5776

CENPC (9Q1) Rabbit Monoclonal Antibody

CENP-C; CENPC1; hcp-4; ICEN7; MIF2;

Affinity-chromatography

常规抗体

CENPC

CENPC1, ICEN7

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

1060

Q03188

WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 IP 1:50 FC 1:200

107kDa

Rabbit IgG

CENPC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus. Chromosome, centromere, kinetochore. Chromosome, centromere. Note=Localizes exclusively in the kinetochore domain of centromeres.

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

现货