产品名称
Retinoic Acid Receptor gamma (8K1) Rabbit Monoclonal Antibody
别名
NR1B3; RAR gamma; RARC; Rarg;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P13631
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200
注意事项
Retinoic Acid Receptor gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in aortic endothelial cells (at protein level).
功能
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
