RM5772

KAT8 / MYST1 / MOF (9E16) Rabbit Monoclonal Antibody

hMOF; MOF; MOZ; MYST1; SAS2; SAS3; YBF2; YBF2/SAS3; ZC2HC8;

Affinity-chromatography

常规抗体

KAT8

MOF, MYST1

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

84148

Q9H7Z6

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:100 FC 1:100

52kDa

Rabbit IgG

KAT8 / MYST1 / MOF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus. Chromosome

Histone acetyltransferase which may be involved in transcriptional activation (PubMed:12397079, PubMed:22020126). May influence the function of ATM (PubMed:15923642). As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac (PubMed:16227571, PubMed:16543150, PubMed:21217699, PubMed:22547026, PubMed:22020126). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852, PubMed:22547026). That activity is less specific than the one of the MSL complex (PubMed:20018852, PubMed:22547026). Can also acetylate TP53/p53 at 'Lys-120'.

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