产品名称
SSX6 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
Q7RTT6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7RTT6/entry
免疫原
Synthesized peptide derived from human SSX6 AA range: 119-169
特异性
This antibody detects endogenous levels of SSX6 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members, rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Aug 2009],
组织表达
Not detected in any normal tissues. Expressed in a melanoma cell line.
功能
function:Could act as a modulator of transcription.,similarity:Belongs to the SSX family.,similarity:Contains 1 KRAB-related domain.,tissue specificity:Not detected in any normal tissues. Expressed in a melanoma cell line.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
