产品名称
Syntrophin alpha 1 (11M13) Rabbit Monoclonal Antibody
别名
Alpha 1 syntrophin; LQT12; SNT1; Snta1; Syntrophin 1; TACIP1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q13424
免疫原
A synthetic peptide of human Syntrophin alpha 1
稀释度
WB: 1:1000-1:5000 IHC: 1:50 ICC/IF: 1:50 FC: 1:50
注意事项
Syntrophin alpha 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta
细胞定位
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions
功能
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity).
