RM5748

CHD1L (17T3) Rabbit Monoclonal Antibody

ALC1; chd1l; CHDL;

Affinity-chromatography

常规抗体

CHD1L

WB

Human,Mouse

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

9557

Q86WJ1

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:200

101kDa

Rabbit IgG

CHD1L Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Frequently overexpressed in hepatomacellular carcinomas.

Nucleus. Note=Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.

DNA helicase which plays a role in chromatin-remodeling following DNA damage (PubMed:19661379, PubMed:29220653). Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair (PubMed:19661379). Able to catalyze nucleosome sliding in an ATP-dependent manner (PubMed:19661379). Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding (PubMed:19661379, PubMed:29220653).

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