产品名称
PHOX2B (7H13) Rabbit Monoclonal Antibody
别名
NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q99453
稀释度
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200
注意事项
PHOX2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in neuroblastoma, brain and adrenal gland
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
功能
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.
