RM5743

PGDH (9T2) Rabbit Monoclonal Antibody

15-PGDH; Hpgd; PGDH; PGDH1; PHOAR1; SDR36C1;

Affinity-chromatography

常规抗体

HPGD

PGDH1, SDR36C1

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

3248

P15428

Recombinant protein of human Prostaglandin dehydrogenase 1

WB: 1:1000-1:5000 IHC: 1:500 ICC/IF: 1:50 FC: 1:20

25kDa

29kDa

Rabbit IgG

PGDH Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Detected in colon epithelium (at protein level).

Cytoplasm.

Primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their corresponding oxidized metabolites (Probable). Prostaglandin inactivation, catalyzes the first step in the catabolic pathway of the prostaglandins. Contributes to the regulation of events that are under the control of prostaglandin levels (PubMed:15574495, PubMed:16828555, PubMed:8086429). Catalyzes the NAD- dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (PubMed:10837478). Converts 11(R)-HETE to 11-oxo-5,8,12,14-(Z,Z,E,Z)- eicosatetraenoic acid (ETE) (PubMed:21916491). Has hydroxylated docosahexaenoic acid metabolites as substrates (PubMed:25586183). Converts resolvins E1, D1 and D2 to their oxo products which represents a mode of resolvins inactivation and stabilizes their anti-inflammatory actions (PubMed:16757471, PubMed:22844113).

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