产品名称
Band 3 / CD233 (12R8) Rabbit Monoclonal Antibody
别名
AE1; BND3; CD233; DI; EMPB3; EPB3; FR; RTA1A; SLC4A1; SW; WD; WD1; WR;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P02730
免疫原
A synthetic peptide of human Band 3
稀释度
WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20
注意事项
Band 3 / CD233 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in erythrocytes (at protein level).
细胞定位
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney.
功能
Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
