产品名称
PHOX2B (7H13) Rabbit Monoclonal Antibody
别名
NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q99453
注意事项
PHOX2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in neuroblastoma, brain and adrenal gland
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
功能
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.
