产品名称
PSB9 / LMP2 (10V5) Rabbit Monoclonal Antibody
别名
Beta1i; LMP2; PSMB 9; PSMB6i; PSMB9; RING12;
纯度
Affinity-chromatography
蛋白名称
LMP2, PSMB6i, RING12
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P28065
稀释度
WB 1:1000~1:5000 ICC/IF 1:50~1:200 FC 1:50
注意事项
PSB9 / LMP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809}. Nucleus
功能
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.