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Gephyrin (8G16) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5702
产品名称
Gephyrin (8G16) Rabbit Monoclonal Antibody
别名
Domain E; Domain G; GEPH; GPH; GPHN; GPHRYN;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
GPHN
蛋白名称
GPH, KIAA1385
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
10243
Human Swissprot No.
Q9NQX3
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
预测分子量
80kDa
同种型
Rabbit IgG
注意事项
Gephyrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell junction, synapse, postsynaptic cell membrane; Lipid-anchor; Cytoplasmic side. Cell membrane {ECO:0000250|UniProtKB:Q03555}; Lipid-anchor {ECO:0000250|UniProtKB:Q03555}; Cytoplasmic side {ECO:0000250|UniProtKB:Q03555}. Cytoplasm, cytosol. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q03555}. Cell projection, dendrite. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q8BUV3}. Note=Cytoplasmic face of glycinergic postsynaptic membranes (By similarity). Forms clusters at synapses (PubMed:25025157). {ECO:0000250|UniProtKB:Q03555, ECO:0000269|PubMed:25025157}
功能
Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed:25025157, PubMed:26613940).
期货
现货

Western blot analysis of Gephyrin expression in 293T cell lysate.

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