RM5678

Glucose 6 phosphate isomerase (18Z16) Rabbit Monoclonal Antibody

AMF; NLK; PGI; PHI; GNPI; SA-36; GPI;

Affinity-chromatography

常规抗体

GPI {ECO:0000303|PubMed:2387591, ECO:0000312|HGNC:HGNC:4458}

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

2821

P06744

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

63kDa

Rabbit IgG

Glucose 6 phosphate isomerase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Cytoplasm. Secreted

In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (PubMed:28803808). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility (PubMed:11437381). Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons (PubMed:3352745, PubMed:11004567). It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (PubMed:3352745, PubMed:11004567).

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