RM5676

EB3 (3K10) Rabbit Monoclonal Antibody

EB3; EBF3; MAPRE3; RP/EB Family; RP3;

Affinity-chromatography

常规抗体

MAPRE3

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

22924

Q9UPY8

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

32kDa

Rabbit IgG

EB3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Predominantly expressed in brain and muscle.

Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Detected at the plus end of microtubules

Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non- centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:28814570). Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (PubMed:28814570). May play a role in cell migration (By similarity).

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