产品名称
Matrin 3 (1G4) Rabbit Monoclonal Antibody
别名
KIAA0723; Matr3; Matrin3; MPD2; VCPDM;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P43243
免疫原
A synthetic peptide of human Matrin 3
稀释度
WB: 1:2000-1:10000 IHC: 1:200 ICC/IF: 1:50-1:200 FC: 1:50
注意事项
Matrin 3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:
28712728). May bind to specific miRNA hairpins (PubMed:
28431233).
