产品名称
GABA A Receptor beta 1 (8U7) Rabbit Monoclonal Antibody
别名
GABA-A receptor, beta-1 polypeptide; Gabrb-1; GABRB1; GARB1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P18505
注意事项
GABA A Receptor beta 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:P50571}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P50571}. Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P50571}
功能
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.