RM5630

PDE4D (10C9) Rabbit Monoclonal Antibody

DPDE3; HSPDE4D; PDE43; Pde4d; PDE4DN2; STRK1;

Affinity-chromatography

常规抗体

PDE4D

DPDE3

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

5144

Q08499

WB 1:500~1:2000

91kDa

Rabbit IgG

PDE4D Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle

Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity) Colocalized with SHANK2 to the apical membrane of colonic crypt cells

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

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