产品名称
NDUA5 Rabbit Polyclonal Antibody
蛋白名称
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q16718
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16718/entry
Mouse Swissprot No.
Q9CPP6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CPP6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63362
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
NDUA5 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014],
组织表达
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
信号通路
Oxidative phosphorylation;Alzheimer's disease;Parkinson's disease;Huntington's disease;
功能
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA5 subunit family.,subunit:Complex I is composed of 45 different subunits.,tissue specificity:Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
