产品名称
NDUAB Rabbit Polyclonal Antibody
蛋白名称
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Complex I-B14.7) (CI-B14.7) (NADH-ubiquinone oxidoreductase subunit B14.7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86Y39
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86Y39/entry
Mouse Swissprot No.
Q9D8B4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D8B4
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q80W89
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
NDUAB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010],
组织表达
Heart,Platelet,Uterus,
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side .
信号通路
Oxidative phosphorylation;
功能
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,sequence caution:Erroneous CDS prediction.,similarity:Belongs to the complex I NDUFA11 subunit family.,subunit:Complex I is composed of 45 different subunits.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
