产品名称
SynGAP (13A7) Rabbit Monoclonal Antibody
别名
MRD5; p135 SynGAP; RASA1; RASA5; SYNGAP1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q96PV0
免疫原
A synthetic peptide of human SynGAP
稀释度
WB: 1:1000-1:2000 ICC/IF: 1:20 FC: 1:20
注意事项
SynGAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
