产品名称
NDUAA Rabbit Polyclonal Antibody
蛋白名称
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95299
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95299/entry
Mouse Swissprot No.
Q99LC3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99LC3
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q561S0
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
NDUAA Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a component of 42 kDa complex I, the first enzyme complex in the electron transport chain of mitochondria. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. A mutation in this gene was found in an individual with Leigh syndrome. [provided by RefSeq, Apr 2016],
组织表达
Brain,Placenta,Skin,
细胞定位
Mitochondrion matrix .
信号通路
Oxidative phosphorylation;Alzheimer's disease;Parkinson's disease;Huntington's disease;
功能
cofactor:Binds 1 FAD per subunit.,function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA10 subunit family.,subunit:Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
