产品名称
NNTM Rabbit Polyclonal Antibody
蛋白名称
NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q13423
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13423/entry
Mouse Swissprot No.
Q61941
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61941
免疫原
Synthesized peptide derived from human protein . at AA range: 240-320
特异性
NNTM Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016],
组织表达
Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues.
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein ; Matrix side .
信号通路
Nicotinate and nicotinamide metabolism;
功能
catalytic activity:NADPH + NAD(+) = NADP(+) + NADH.,function:The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.,similarity:In the C-terminal section; belongs to the PNT beta subunit family.,similarity:In the N-terminal section; belongs to the AlaDH/PNT family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
