产品名称
CD97 (16U13) Rabbit Monoclonal Antibody
别名
ADGRE5; Adhesion G protein-coupled receptor E5; CD97 antigen; Leukocyte antigen CD97; Seven span transmembrane protein; TM7LN1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P48960
免疫原
A synthetic peptide of human CD97
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:20 IP: 1:20
注意事项
CD97 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid
细胞定位
Cell membrane {ECO:0000250|UniProtKB:Q9Z0M6}; Multi-pass membrane protein
功能
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
