产品名称
Claudin 4 (6G15) Rabbit Monoclonal Antibody
别名
CLD4; CLDN4; CPE- receptor; CPE-R; CPER; CPETR1; Clostridium perfringens enterotoxin receptor; WBSCR8; Williams-Beuren syndrome chromosome region 8 protein;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O14493
稀释度
WB 1:500~1:1000 IHC 1:100~1:500 IP 1:20
注意事项
Claudin 4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell junction, tight junction {ECO:0000250|UniProtKB:O35054}. Cell membrane; Multi-pass membrane protein. Note=CLDN4 is required for tight junction localization in the kidney. {ECO:0000250|UniProtKB:O35054}
功能
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
