产品名称
Aspartate Aminotransferase (10O16) Rabbit Monoclonal Antibody
别名
Aspartate aminotransferase 1; ASTQTL1; cAspAT; cCAT; GIG18; Glutamate oxaloacetate transaminase 1; GOT1; Growth inhibiting protein 18; SGOT; Transaminase A;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P17174
免疫原
A synthetic peptide of human Aspartate Aminotransferase
稀释度
WB: 1:1000 IHC: 1:20-1:100 ICC/IF: 1:100 FC: 1:20-1:100
注意事项
Aspartate Aminotransferase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
