产品名称
MYO5B Rabbit Polyclonal Antibody
蛋白名称
Unconventional myosin-Vb
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9ULV0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ULV0/entry
Mouse Swissprot No.
P21271
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P21271
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P70569
免疫原
Synthesized peptide derived from human protein . at AA range: 1120-1200
特异性
MYO5B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009],
功能
disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
