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MUM1 (9F19) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5480
产品名称
MUM1 (9F19) Rabbit Monoclonal Antibody
别名
LSIRF; Multiple myeloma oncogene 1; NF-EM5; IRF4; MUM1; Transcriptional activator PIP;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
IRF4
蛋白名称
MUM1
推荐应用
WB
反应种属
Human
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
3662
Human Swissprot No.
Q15306
稀释度
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:100 FC 1:120
预测分子量
52kDa
同种型
Rabbit IgG
注意事项
MUM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Lymphoid cells.
细胞定位
Nucleus.
功能
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA- 3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
期货
现货

Western blot analysis of MUM1 expression in Daudi cell lysate.

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