产品名称
HSD11B1 (17P16) Rabbit Monoclonal Antibody
别名
11-DH; 11-beta-HSD1; HSD11B1; HSD11; HSD11L; 11 beta HSD1;
纯度
Affinity-chromatography
蛋白名称
HSD11, HSD11L, SDR26C1
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P28845
注意事项
HSD11B1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed. Highest expression in liver.
细胞定位
Endoplasmic reticulum membrane; Single-pass type II membrane protein
功能
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone (PubMed:
10497248). Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity).
