产品名称
PLGF (16R19) Rabbit Monoclonal Antibody
别名
Pgf; PGFL; PIGF; Placenta growth factor; Placental growth factor, vascular endothelial growth factor related protein; PlGF; PlGF2; SHGC 10760;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P49763
免疫原
A synthetic peptide of human PLGF
注意事项
PLGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas
细胞定位
Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
功能
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
