RM5413

CXCR3 (19A9) Rabbit Monoclonal Antibody

C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183; GPR9; CXCR3;

Affinity-chromatography

常规抗体

CXCR3

GPR9

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

2833

P49682

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50

41kDa

Rabbit IgG

CXCR3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level).

[Isoform 1]: Cell membrane; Multi-pass membrane protein

[Isoform 1]: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G- protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response. [Isoform 3]: Mediates the activity of CXCL11.

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